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Medical Research

Schizophrenia: 10 new genes identified

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In what is defined as one of the largest DNA sequencing studies related to schizophrenia, a group of researchers led by Tarjinder Singh has discovered 10 new genes implicated in the development of this pathology with a method called “whole-exome sequencing.” The researchers used genetic data from more than 125,000 people to obtain various information regarding the genetic basis of schizophrenia itself. The results of the research were then presented at the annual meeting of the American Society of Human Genetics 2019 in Houston.

One of the reasons that led researchers to use DNA sequencing to obtain information on schizophrenia is that for this disease, in the last fifty years, there has been quite limited progress regarding the development of new drugs. However, the use of new genetic techniques is proving very useful, in recent years, in many fields and the same researchers believe that useful results can also be obtained to discover mechanisms underlying schizophrenia.

The latter is one of the psychiatric disorders not yet fully understood. It is believed, however, that its development can be accelerated by disorders concerning some genes that encode certain proteins. Because these are rare genetic changes, the researchers used a very large set of people. Of the 125,000 people analyzed, 25,000 of them had been diagnosed with schizophrenia. People came from all five continents.

Following the analyzes, the researchers identified 10 genes that, once they stopped their functions, caused an increased risk of schizophrenia, as Singh himself stated in the press release. Two of these 10 genes encoded glutamate receptors, indicating that these receptors could potentially be a target for future therapies against schizophrenia.

Johnathan Flint

Johnathan is a recent graduate of the Missouri University of Science and Technology with a Bachelor of Medicine, and is an avid reader of numerous medical journals. He recently joined Health Shiner as an editor, researcher and content contributor, and brings a great deal of knowledge and wisdom to our reporting.

2462 White Oak Drive, Weston Missouri, 64098
Ph: 816-640-5682
Email: [email protected]
Johnathan Flint
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Medical Research

Tobacco also linked to worse mental health according to a new study

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Often, when reference is made to the damage of cigarette smoking, mental health is hardly ever thought about, and yet cigarettes are also bad for you. This is suggested by a study by Professor Hagai Levine of the Hebrew University of Jerusalem published in PLOS ONE.

Levine and colleagues carried out a survey of 2000 Serbian university students from different social and economic backgrounds. The researchers found that students who smoked showed higher rates of clinical depression than their non-smoking peers, two to three times.

Taking into consideration only the students of the University of Pristina, the researchers found that 14% of the smoking students suffered from depression compared to 4% of the non-smoking peers, while for the University of Belgrade the percentages were 19% compared to 11% respectively.

The same students who smoked also showed lower mental health scores than non-smokers. According to Levine, this study adds further evidence that smoking and depression may be linked; although there is no direct evidence yet that smoking causes depression, it can be said that tobacco seems to have a non-positive effect on mental health.

Johnathan Flint

Johnathan is a recent graduate of the Missouri University of Science and Technology with a Bachelor of Medicine, and is an avid reader of numerous medical journals. He recently joined Health Shiner as an editor, researcher and content contributor, and brings a great deal of knowledge and wisdom to our reporting.

2462 White Oak Drive, Weston Missouri, 64098
Ph: 816-640-5682
Email: [email protected]
Johnathan Flint
Continue Reading

Medical Research

One can evaluate hearing quality by analyzing pupil dilation according to researchers

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It may prove to be a new and effective hearing test developed by a team of neuroscientists at the University of Oregon. According to a statement on the university’s website, it is possible to assess a person’s hearing level by measuring pupil dilation.

According to the same statement, this approach could be useful to understand the quality of hearing in infants, young adults with disabilities and adults with stroke or other diseases and in general in those people for whom direct responses are not possible. The researchers performed experiments on 31 adults by monitoring the size of their pupils with eye detection technology. The detection took place while the same people performed a hearing test and while staring at an object at a monitor.

The study, published in the Journal of the Association for Research in Otorhinolaryngology, explains that this system is inspired by a discovery made by the main author of the study, Avinash Singh Bala, 10 years ago when he noticed changes in the pupils of barn owls in response to unexpected noises in their natural environment.

“What we discovered was that pupil dilation was as sensitive as the button-press method,” Bala explains. “We had presented the first data analyses at the conferences and there was a lot of resistance to the idea that by using an involuntary response we could get results as good as the button-pressing data.”

Johnathan Flint

Johnathan is a recent graduate of the Missouri University of Science and Technology with a Bachelor of Medicine, and is an avid reader of numerous medical journals. He recently joined Health Shiner as an editor, researcher and content contributor, and brings a great deal of knowledge and wisdom to our reporting.

2462 White Oak Drive, Weston Missouri, 64098
Ph: 816-640-5682
Email: [email protected]
Johnathan Flint
Continue Reading

Medical Research

New peanut butter with probiotics developed by scientist

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A new peanut butter that allows you to acquire probiotic positives was developed by researcher Dan Perlman. Probiotics are microorganisms that live in the digestive system that help to promote digestion, produce important hormones and vitamins and generally strengthen the immune system.

For years, Perlman has been looking for new ways to “pack” probiotics into food to allow people to acquire them without using pills or third-party capsules. Probiotics need to be ingested alive to take advantage of their positive characteristics but if there is not enough water or other energy sources in the food to support these bacteria, they die quickly and are therefore useless once ingested.

Walnut butters seem to be unsuitable for cramming live probiotics as they contain very little water. However, the researcher noted that when freeze-dried peanut butter bacteria come in, the bacteria themselves remain “suspended” in a sort of deep sleep, still alive but ready to get back to work and “wake up” once they are ingested by people.

This is because they remain trapped in the structure of the fat matrix of these foods, a rather crystalline fat.

In the new peanut butter developed by the researcher, there are 500 million to one billion bacteria in a two-spoon portion, the amount of a probiotic pill.

Now the researcher himself is looking for a way to make this new peanut butter with probiotics for commercial use.

Johnathan Flint

Johnathan is a recent graduate of the Missouri University of Science and Technology with a Bachelor of Medicine, and is an avid reader of numerous medical journals. He recently joined Health Shiner as an editor, researcher and content contributor, and brings a great deal of knowledge and wisdom to our reporting.

2462 White Oak Drive, Weston Missouri, 64098
Ph: 816-640-5682
Email: [email protected]
Johnathan Flint
Continue Reading
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